Intrahepatic Cholangiocarcinoma in a Patient with Alcoholic Liver Cirrhosis and Markedly Elevated Serum Alpha-Fetoprotein

Hepatocellular carcinoma (HCC) is considered the leading cause of primary liver malignancy, however, a tumor arising from biliary tree should be always kept among differential diagnosis. Cholangiocarcinoma (CCA) group malignancies that represents 10-20% all masses being perihilar cholangiocarcinoma most common and intrahepatic less subtype. Important biomarkers such as serum alpha-fetoprotein (AFP) are commonly measured. An elevated AFP > 400 ng/mL very specific for HCC. On contrary, levels rarely exceed 20 in patients with cholangiocarcinoma. We report case patient markedly who was found to have ICC.